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- ---
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- license: mit
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ license: mit
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+ language:
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+ - en
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+ pretty_name: ABX-CT-010 Cycling Strategy Collapse
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+ tags:
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+ - antibiotics
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+ - stewardship
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+ - cycling
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+ - resistance
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+ - mdr
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+ - tabular
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+ task_categories:
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+ - tabular-classification
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+ size_categories:
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+ - n<1k
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+ ---
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+
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+ ABX-CT-010 Cycling Strategy Collapse
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+
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+ Purpose
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+
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+ Detect when antibiotic rotation stops controlling resistance.
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+
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+ Core pattern
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+
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+ - stress_index high
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+ - cycle_exposure_index high
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+ - burden_gap stays high across different cycle drugs
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+ - mdr_marker rises and stays high
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+ - later clinical_failure_flag appears
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+
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+ Files
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+
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+ - data/train.csv
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+ - data/test.csv
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+ - scorer.py
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+
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+ Schema
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+
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+ Each row is one cycle timepoint in a within series rotation history.
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+
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+ Required columns
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+
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+ - row_id
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+ - series_id
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+ - timepoint_d
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+ - cycle_id
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+ - drug_in_cycle
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+ - stress_index
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+ - cycle_exposure_index
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+ - population_resistance_burden
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+ - expected_burden_under_cycling
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+ - burden_gap
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+ - mdr_marker
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+ - mic_to_active_drug_fold_vs_baseline
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+ - clinical_failure_flag
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+ - source_type
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+ - cycling_collapse_signal
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+ - earliest_cycling_collapse
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+
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+ Labels
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+
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+ - cycling_collapse_signal
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+ - 1 for rows at or after first confirmed collapse point
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+
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+ - earliest_cycling_collapse
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+ - 1 only for the first collapse row in that series
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+
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+ Scorer logic in v1
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+
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+ - candidate collapse point
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+ - stress_index at least 0.80
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+ - cycle_exposure_index at least 0.80
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+ - burden_gap at least 0.25 at two consecutive points
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+ - consecutive points must be different drug_in_cycle values
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+ - mdr_marker at least 0.60 and up at least 0.10 vs baseline
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+ - exclude burden_gap spike then snapback artifacts
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+ - confirmation
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+ - clinical_failure_flag equals 1 later in series
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+
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+ Evaluation
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+
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+ Run
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+
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+ - python scorer.py --path data/test.csv